IndraLab

Statements

USP28 activates HYCC1. 3 / 3
| 3
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"The experiments in vitro confirmed that USP28 could promote cell proliferation, migration, and invasion in the HCC cell lines."
37450415
reach
"Furthermore, two deubiquitinating enzymes, USP9X and USP28, have significant expression in HCC and could similarly promote HCC cell proliferation by regulating the activity of this pathway (128, 129)."
38634048
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"Additionally, our molecular biology experiments validated that the knockdown of USP28 substantially reduced the proliferative and invasive abilities of the HCC cell lines.Conclusions: Our study suggests that USP28 could potentially serve as a biomarker for cancer immunologic infiltration and poor prognosis, with potential applications in developing novel cancer treatment strategies."
37450415