IndraLab

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USP18 deubiquitinates SNAI1. 4 / 4
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"A previous study has demonstrated that USP18 can promote the proliferation, migration, and invasion of colorectal cancer cells by deubiquitinating and stabilizing Snail1 protein ( Huang et al., 2020 )[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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"In a similar vein, USP18 was determined to bolster tumour proliferation, migration, and invasion by deubiquitinating ZEB1 and Snail1 and solidifying their expression [18, 19]."

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"Moreover, USP18 can deubiquitinate and stabilize the Snail1 protein, facilitating colorectal cancer proliferation, migration, and invasion [13] ."

"Conclusion: <span class="match term0">USP18</span> could promote the proliferation, migration, and invasion of colorectal cancer by deubiquitinating and stabilizing the <span class="match term1">Snail1</span> protein in colorectal cancer."