IndraLab

Statements

USP11 deubiquitinates XPC. 3 / 4
1 | 3
reach
"Notably, USP11 plays a key role in DNA damage repair depending on its catalytic activity, for example, Xia Ting et al. [20] found that USP11 acts as a histone deubiquitinase in chromatin reorganization during DNA repair, Palak Shah et al. [21] found that USP11 regulates UV-induced DNA damage repair by deubiquitinating XPC, and Tanggang Deng et al. [32] identified that the deubiquitylation and stabilization of p21 by USP11 is essential for cell cycle progression and DNA damage responses."
35715413
reach
"USP11 knockdown in HaCaT cells increased ubiquitination of XPC as compared to control cells, suggesting that USP11 is important in maintaining NER capacity, as USP11 mediates XPC deubiquitination at the chromatin following UVB damage [XREF_BIBR]."
30831436
reach
"Regulation of XPC deubiquitination by USP11 in repair of UV induced DNA damage."
32364424