IndraLab

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AMPK inhibits KCNH2. 2 / 2

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"Pharmacological activation of AMPK with AICAR or with phenformin inhibited hERG currents in Xenopus oocytes, an effect abrogated by AMPK inhibitor compound C. (gammaR70Q) AMPK enhanced the Nedd4-2-dependent downregulation of hERG currents."

23716168

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"The multi targeted TKi sunitinib showed decreased cardiomyocyte viability, AMPK inhibition, increased lipid accumulation, disrupted beat pattern, and hERG block."

23707608

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IndraLab

Statements

AMPK inhibits KCNH2. 2 / 2

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