IndraLab

Statements

USP15 activates RI. 2 / 2
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"Most of the alternative splicing events were downregulated, while the RI event was upregulated by USP15 and USP4, consistent with our previous finding that the depletion of USP15 and USP4 results in the intron retention of genes such as Bub1 and α-tubulin [1]."
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"USP15 and UCH37, and presumably also USP11, deubiquitylate TβRI through their association with Smad7, and thus prevent degradation of TβRI [54–56] ."
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