IndraLab

Statements

reach
"At the same time, tBHQ activated Nrf2 mediated inhibition of the p65 nuclear factor-kappaB pathway and activation of peroxisome proliferator activated receptor-gamma, which play important roles in regulating macrophage polarization."
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eidos
"We found that tBHQ reduced NLRP3 , p65 and TXNIP and increased TRX expression in aged EPCs ( Figure 6E , 6H , 6I ) , while silencing Nrf2 in young EPCs upregulated NLRP3 , p65 and TXNIP and downregulated TRX expression ( Figure 6E , 6J , 6K ) ."
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reach
"However, these studies demonstrated that tBHQ inhibited NFkappaB p65 transcriptional activity in activated Jurkat T cells [XREF_BIBR]."
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