IndraLab

Statements

Gliotoxin inhibits NFKB1. 3 / 3
1 | 2
ctd
No evidence text available
14527959
reach
"Indeed, GT was shown to block NFkB activation in B and T cells by preventing IkBα degradation (106) and later on to kill CD8 T cells, preventing cytotoxic T cell-mediated cytotoxicity (90)."
30459771
reach
"Thus, the contribution of GT during IA could be related not only to its ability to favor immune evasion, but, in addition, to an exacerbation of tissue damage induced by neutrophils in corticosteroid-treated patients.Concerning other PMN cells, it was reported that inhibition of NFkB by GT increases eosinophil apoptosis mediated by TNF-α (95)."
30459771