IndraLab

Statements

USP7 deubiquitinates TPP1. 7 / 7
1 | 6
reach
"Because TPP1 is ubiquitinated and the co-immunoprecipitation data suggested that it is a USP7 substrate, we next tested whether USP7 indeed deubiquitinates TPP1."
25172512
reach
"Together, these data indicate that USP7 deubiquitinates TPP1."
25172512
reach
"Addition of USP7 (WT)-3xFLAG but not USP7 (C223S)-3xFLAG reduced TPP1 ubiquitination (XREF_FIG C, lanes 5 and 6), confirming that TPP1 is a USP7 substrate."
25172512
reach
"We identify amino acids in TPP1 and USP7 that are critical for their interaction and multiple lysines within TPP1 that are oligo ubiquitinated and deubiquitinated by USP7."
25172512
reach
"Therefore, both in vivo and in vitro evidence indicates that TPP1 is deubiquitinated by USP7."
25172512
reach
"TPP1 Is Deubiquitinated by USP7."
25172512
ubibrowser
"Review"
27775833