IndraLab

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"As YB-1-mediated translational regulation is dependent on the molar ratio of YB-1 to its binding mRNA [12,13] , it was speculated that translational activation resulted from alteration of the amount o[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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"YB-1 binds to GluR2 mRNA and CaM1 mRNA in the brain and regulates their translational levels in an activity dependent manner."

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"In the brain, the expression of YB-1 is closely associated with development, and YB-1 binds to GluR2 mRNA and CaM1 mRNA to regulate their levels of translation in an activity-dependent manner [4] ."

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"Therefore we examined the effect of nicotine on the amounts of YB-1-bound GluR2 mRNA and YB-1-associated ribosomal protein S6 in the heavier-sedimenting fractions."

sparser
"As YB-1-mediated translational regulation is dependent on the molar ratio of YB-1 to its binding mRNA [12,13] , it was speculated that translational activation resulted from alteration of the amount o[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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"These results suggest that in the brain of growing mice, YB-1 binds to GluR2 and CaM1 mRNAs and regulates their translation in an activity dependent manner."

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"Stimulation of α7-nAChR activates the PI3K/Akt pathway, and phosphorylation may induce conformational changes in some YB-1 molecules that are bound to GluR2 mRNA, thus releasing them from the mRNA, ex[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"