IndraLab

Statements

SIRT7 binds USP39. 14 / 14
6 | 2 6
sparser
"Moreover, Dong et al.’s study revealed that USP39 interacts with SIRT7, which deacetylates USP39 to enhance its stability, thereby further promoting HCC development ( xref )."
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biogrid
No evidence text available
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No evidence text available
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No evidence text available
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sparser
"The results of Co-IP revealed that Flag-USP39 was significantly enriched in the precipitates of Myc-SIRT7 and vice versa, which indicated that USP39 interacted with SIRT7 in CaSki and SiHa cells (Fig.  xref B)."
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biogrid
No evidence text available
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biogrid
No evidence text available
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reach
"The binding between USP39 and SIRT7 was evaluated by western blot using anti-Flag tag (ab205606, 1/3000, abcam) or anti-Myc (ab32, 1/3000, abcam) antibodies."
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"In addition, we also evaluated the interaction between SIRT7 and USP39 in human CSCC tissues."
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sparser
"Co-immunoprecipitation indicated that SIRT7 interacted with USP39 (Additional file xref : Fig S2A)."
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sparser
"After confirming that SIRT7 and USP39 interacts with each other and that SIRT7 facilitates USP39 stability via deacetylation, we next evaluated the expression level and functional role of USP39 in CSCC tumorigenesis."
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sparser
"In the above experiment, we have shown that SIRT7 interacts with USP39 and enhance protein stability of USP39 via deacetylation and that USP39 regulates SIRT7 expression."
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reach
"In addition, we also evaluated the interaction between SIRT7 and USP39 in human CSCC tissues."
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biogrid
No evidence text available
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