IndraLab

Statements


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sparser
"In this study, we examined that METTL3 knockdown significantly decreased the binding of HNRNPD to USP4 pre-mRNA(Figure xref N and xref B); however, the interaction between ELAVL1 and USP4 pre-mRNA were not significantly changed(Figure xref O and xref C)."

sparser
"Taken together, these results suggested m 6 A methylation reduces USP4 mRNA stability by promoting the binding of HNRNPD to USP4 mRNA."

reach
"In this study, we examined that METTL3 knockdown significantly decreased the binding of HNRNPD to USP4 pre-mRNA; however, the interaction between ELAVL1 and USP4 pre-mRNA were not significantly changed."

reach
"Taken together, these results suggested m 6 A methylation reduces USP4 mRNA stability by promoting the binding of HNRNPD to USP4 mRNA."

sparser
"The mRNA of USP4 can bind to the RNA-binding protein HNRNPD, with its mRNA A2696 checkpoint modified by m6A via METTL3 and YTHDF2, resulting in mRNA degradation ( xref )."