IndraLab

Statements

SB 203580 inhibits MAPK8. 3 / 5
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"Further experiments showed that SB203580 was not able to suppress the mobility shift in Jnk1 and Jnk2 single knockout cells, indicating that both Jnk kinases act redundantly to phosphorylate B-Myb (XREF_SUPPLEMENTARY)."
23449447
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"To test that SB203580 was not inhibiting JNK1 activity as well, we measured JNK1 activity and found that SB203580 had little effect on drug induced JNK1 activation."
11734304
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"The SAP kinases SAPK1 gamma and JNK1, SAPK3 and SAPK4 are not inhibited by SB 203580, because they have methionine in the position equivalent to Thr106 in the ATP binding region of SAPK2a and p38 and SAPK2b and p38 beta 2."
9653550