IndraLab

Statements

SB 203580 inhibits MAPK8. 6 / 10
2 | 6
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"Further experiments showed that SB203580 was not able to suppress the mobility shift in Jnk1 and Jnk2 single knockout cells, indicating that both Jnk kinases act redundantly to phosphorylate B-Myb (XREF_SUPPLEMENTARY)."
23449447
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"To test that SB203580 was not inhibiting JNK1 activity as well, we measured JNK1 activity and found that SB203580 had little effect on drug induced JNK1 activation."
11734304
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"Firstly, cells were cultivated for a period of 16 h using either 10 μM SP600125 or 10 μM SB203580, and next, incubated at the concentration of 0.4 μM of brusatol for 8 h. Study shown in Fig. 4 A and B[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
28455228
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"SB203580 also strongly inhibited the JNK1 isoform."
20132813
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"Thus, after an osmotic stress induced by 0.4 M sorbitol for 10 min, immunoblot analysis demonstrates that 25 μM SB203580 and 25 μM SP600125 reduced p-p38 and p-JNK over 75% of the control value (data [MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
20691164
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"The SAP kinases SAPK1 gamma and JNK1, SAPK3 and SAPK4 are not inhibited by SB 203580, because they have methionine in the position equivalent to Thr106 in the ATP binding region of SAPK2a and p38 and SAPK2b and p38 beta 2."
9653550