IndraLab

Statements

EGFR phosphorylates SRC on tyrosine. 3 / 4
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"We also review the complex regulation by tyrosine phosphorylation by epidermal growth factor receptor (EGF-R), Janus Kinase 3 (JAK3) and Src and the role of phosphatases."
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"This revealed that EGFR became phosphorylated at the c-Src specific tyrosine phosphorylation site Tyr845 within 5 min of aldosterone treatment ( Fig. 7 A )."
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"The activated EGFR signals through phosphorylated tyrosine residues to stimulate multiple pathways, including mitogen activated protein kinase (MAPK), phosphatidylinositol 3-kinase (PI3K)/Akt, signal transducers and activators of transcription (STAT), phospholipase C, and Src and focal adhesion kinase (Src and FAK) pathways."
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