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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

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Statements

Bicuculline inhibits HCN1. 1 / 1

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"In neurons from HCN1 knockout mice the enhancement of EPSP summation by bicuculline was ~ 3-fold greater than observed in cells from wild type mice (see XREF_SUPPLEMENTARY); bicuculline increased EPSP5 : EPSP1 by ~ 12.9 +/- 5.7% in control animals and by 37.3 +/- 5.8% in HCN1 knockouts (n = 6 & 5, respectively; P < 0.05)."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...