IndraLab

Statements

reach
"Additionally, USP22 downregulates transferrin receptor (TFRC) transcription by removing H2B lysine 120 ubiquitination (H2BK120ub) from TFRC transcription start site (TSS) downstream region, thereby inhibiting Sorafenib‐induced ferroptosis in hepatocellular carcinoma."
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"Recent studies have demonstrated that USP22 can inhibit the transcription of the p21 gene by de-ubiquitinating the transcriptional regulator FBP1, leading to cell proliferation and tumorigenesis [ xref ]."
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"By evaluating the USP22-mediated downregulated genes in tumor cells by Landscape In Silico deletion Analysis (Lisa) [ 22 ], we found that the three transcriptional repressors present in USP22-immunopr[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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