IndraLab

Statements

SIRT1 acetylates KCNMA1. 2 / 2
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reach
"To further investigate the BK channel alpha subunits as potential targets of SIRT1, we found that SIRT1 interacted with BK channel alpha subunits but not the beta2 or beta4 subunits, and the alpha subunit acetylation levels were modulated by inhibition of SIRT1 activity in hippocampus slices, suggesting direct acetylation of the BK channel alpha subunit by SIRT1."
30271963
sparser
"To further investigate the BK channel α subunits as potential targets of SIRT1, we found that SIRT1 interacted with BK channel α subunits but not the β2 or β4 subunits, and the α subunit acetylation levels were modulated by inhibition of SIRT1 activity in hippocampus slices, suggesting direct acetylation of the BK channel α subunit by SIRT1."
30271963