IndraLab

Statements

USP5 inhibits NLRP3. 5 / 5
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"In addition, USP5 mediates the autophagy–lysosomal pathway to promote NLRP3 inflammasome degradation."
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"USP5 attenuates NLRP3 inflammasome activation by promoting autophagic degradation of NLRP3."
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"Baoshan Cai et al. found that USP5 attenuates NLRP3 inflammasome activation by enhancing autophagic degradation of NLRP3 in melanoma [16]."
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"USP5 inhibits the NF-κB signaling pathway and NLRP3 inflammatory body activation when it acts on its substrate IKKβ."
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"In this study, we also found that SaB, a USP5 potential agonist significantly improved SS via USP5/NLRP3 signal pathway.In conclusion, in this study, this study reports a novel regulatory mechanism of[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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