IndraLab

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USP20 decreases the amount of Reactive Oxygen Species. 2 / 2
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"It was found that USP20 knockdown increased lipid ROS levels and ferrous iron levels, while decreased the GSH levels."

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"Consistent with the results identified above, USP20 WT and S132D/S368D reduced cell sensitivity to erastin and increased the GSH levels, while ferrous iron levels decreased and lipid ROS levels of HCC cells (Figures 6H–L)."