IndraLab

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CASP8 decreases the amount of CYLD. 2 / 6

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"Levels of CYLD may be indirectly increased by allosteric inhibition of caspase 8 (which cleaves CYLD) by zVAD-FMK [XREF_BIBR]."

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"Blockade of Caspase 8 activity with the pharmacological inhibitor IETD prevents the loss of full-length CYLD and this correlates with the entry of the NEMO deficient cells into cell death by programmed necrosis."

22848449

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IndraLab

Statements

CASP8 decreases the amount of CYLD. 2 / 6

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