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Hydroxychloroquine leads to the phosphorylation of p38. 3 / 3
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"However, contradicting a previous report (1), we found that verapamil, a TRPML1 calcium channel blocker, was not able to abrogate HCQ- or DC661-induced phosphorylation of p38 (Figure 5H)."
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"Cotreatment of M2 polarized macrophages with Ppt1 inhibitors and BAPTA-AM, a calcium chelator (Figure 5F), or W7, a calmodulin inhibitor (Figure 5G), abrogated HCQ- or DC661-induced phosphorylation of p38."
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"Hydroxychloroquine (10 microM) treatment induced the phosphorylation of ERK, SAPK and JNK and p38."
26082314