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MYC activates USP49. 5 / 5
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"Moreover, it has been recently proposed that USP49 is transcriptionally activated by c-Myc in colorectal cancer cells [8]."
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"These findings suggested that USP49 was transcriptionally activated by c-MYC in CRC cells."
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"Moreover, it has been recently proposed that USP49 is transcriptionally activated by c-Myc in colorectal cancer cells [ xref ]."
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"Here we revealed that Ubiquitin Specific Peptidase 49 ( USP49 ) is transcriptionally activated by c-MYC in colorectal cancer ( CRC ) , and CRC patients with elevated USP49 levels exhibited significantly shorter survival ."
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"These findings suggested that USP49 was transcriptionally activated by c-MYC in CRC cells.To validate the role of USP49 in CRC progression, we depleted endogenous USP49 in HCT116 and SW48 cells by two[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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