IndraLab

Statements


BAP1 activates ASXL1. 2 / 2
| 2

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"Truncated ASXL1 increases BAP1 protein stability, enhances BAP1 recruitment to chromatin and promotes the expression of a pro-leukemic transcriptional signature."

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"Reduced BAP1 activity prevents ASXL1 truncation driven myeloid malignancy in vivo."