IndraLab

Statements

USP13 activates pyroptosis. 4 / 4
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reach
"However, the overexpression of USP13 counteracted spautin-1 improvement of cerebral I/R injury and significantly abolished spautin-1 suppression of autophagy and NLRP3 inflammasome-dependent pyroptosis."
37697221
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"Cerebral I/R significantly reduced the expressions of NLRP3, USP13, beclin 1, and GSDMD-N, which was abolished by spautin-1, indicating that spautin-1 inhibited autophagy and NLRP3 inflammasome-mediated pyroptosis."
35883566
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"A recent study showed that inhibition of USP13 reduced autophagy and ROS accumulation, and attenuated pyroptosis."
37634814
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"However, USP13 overexpression abolished these beneficial effects of spautin-1 and notably counteracted the spautin-1 inhibition of autophagy and NLRP3 inflammasome-mediated pyroptosis."
35883566