IndraLab

Statements

Nicotinamide inhibits CTSB. 3 / 3
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"Nicotinamide inhibits the lysosomal cathepsin b like protease and kills African trypanosomes."
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"have recently shown that nicotinamide itself inhibits the lysosomal cathepsin b-like protease, blocking endocytosis and thereby causing trypanosomal cell death at millimolar concentrations."
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"Kinetoplastids harbor Cathepsin L and B like proteins where Cathepsin B, like proteases in L.donovani, T. cruzi, and T. brucei are inhibited by nicotinamide."
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