IndraLab

Statements


USP15 deubiquitinates TP53. 4 / 4
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"The mechanism for USP15 to block p53 ubiquitination mediated by MDM2 was analyzed."

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"Whereas, USP15 deubiquitinates and stabilizes another p53 ubiquitin ligase, Mdm2, followed by a degradation of p53 [ 25 ]."

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"To examine whether USP15 can deubiquitinate p53, the effect of USP15 on p53 that had been ubiquitinated by overexpressed MDM2 was determined."

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"USP15 deubiquitinates p53."