IndraLab

Statements

Melatonin inhibits RIPK1. 3 / 3
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"Further analysis showed that melatonin significantly attenuated APAP induced activation of the serine/threonine kinase receptor interacting protein 1 (RIP1)."
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"Western blot showed that exposure to FAC resulted in the decrease of anti-apoptotic protein Bcl-2 and the increase of pro apoptotic protein Bax and Cleaved Caspase-3, and necrosis related proteins RIP1 and RIP3, which were significantly inhibited by melatonin treatment."
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"Likewise, luzindole failed to block melatonin induced the reduction of RIP1 and RIP3 in FAC treated BMSCs."
28415572