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Modified USP7 increases the amount of IRS2. 1 / 1
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"By contrast, over-expression of dominant negative USP7 (USP7 CS, where the single cysteine residue in the catalytic center was substituted with serine [19]) decreased IRS-2 protein levels, an effect p[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"