IndraLab

Statements

YOD1 increases the amount of CDK1. 3 / 3
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"Knowing that YOD1 binds to and positively regulates CDK1 protein expression, we firstly examined the level of CDK1 ubiquitination in various TNBC and NTNBC cell lines by immunoprecipitation."
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"It was found that YOD1 increased CDK1 protein level, whereas YOD1 knockdown markedly decreased the CDK1 protein level (Fig. 6B C)."
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"Finally, in vivo study demonstrated that YOD1 knockdown or YOD1 inhibitor could inhibit CDK1 expression and suppress the growth and metastasis of TNBC tumors."
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