IndraLab

Statements


EGF leads to the phosphorylation of EGFR on Y1110. 6 / 6
2 | 4

reach
"Compared with untreated cells, tyrosine phosphorylation of phospholipase C-gamma1 was enhanced by EGF stimulation in glucosylceramide depleted cells, associated with enhanced tyrosine phosphorylation of the EGF receptor at Tyr 1068 and Tyr 1086 stimulated by EGF."

"We have detected 6,600 phosphorylation sites on 2,244 proteins and have determined their temporal dynamics after stimulating HeLa cells with epidermal growth factor (EGF) and recorded them in the Phosida database"

reach
"EGF stimulation increased EGFR phosphorylation on Tyr1173 and Tyr1086 (XREF_FIG and XREF_SUPPLEMENTARY)."

"H322 cells express wild-type EGFR and have no EGFR gene amplification. EGF led to the expected EGFR activation and later to increased levels of EphA2 protein (Fig. 5); both were significantly decreased by the use of the EGFR inhibitor erlotinib."

reach
"TSP1 and its EGF like repeats also increased phosphorylation of EGFR Tyr 845, Tyr 992, Tyr 1045, Tyr 1086, and Tyr 1173, activated phospholipase Cgamma, and increased cell migration."

reach
"EGF stimulation resulted in rapid phosphorylation of EGFR (pEGFR Y1110) which was almost completely blocked by the EGFR kinase inhibitor, tyrphostin (AG1478) (XREF_FIG)."