IndraLab

Statements

USP22 binds YAP1. 5 / 7
2 | 4 1
sparser
"Using IP assays, USP22 interaction with YAP at the endogenous level in A375 melanoma cells was observed ( xref )."
33777217
reach
"In melanoma, USP22 interacts with and deubiquitinates YAP, thereby favoring melanoma cell proliferation."
39135915
reach
"The interaction between USP22 and KDM3A and between KDM3A and YAP1 was further validated."
36700466
reach
"USP22 interacts with and deubiquitinates YAP to prevent YAP turnover [26]."
37349820
reach
"A recent study demonstrated that ubiquitin-specific peptidase 22 (USP22) interacted with and stabilized YAP, which in turn conferred resistance to the BRAF inhibitor vemurafenib and provided new therapeutic avenues to target USP22/YAP as an option for melanoma treatment [224]."
36694209