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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

USP7 inhibits ANXA1. 2 / 2

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"Overall, our findings demonstrate that depletion of HAUSP can decrease ANXA1 stability and cleavage of ANXA1, thereby reducing not only cell apoptosis upon UV but also transmigration of macrophages mediated by Ac2-26."

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"Unlike normal HeLa cells, showing co-localization of HAUSP and ANXA1 in the nucleus by forming nuclear foci in response to UV, the absence of HAUSP abrogated the nuclear localization of ANXA1."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...