IndraLab

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"To gain insight into the functional defects in Mysm1 -/- Puma -/- MPP4s contributing to cell death and downstream lymphopoiesis failures, we performed RNA sequencing (RNA-Seq) of MPPs (Lin - cKit + Sca1 + CD150 -) from Mysm1 -/- Puma -/-, Mysm1 -/- Puma +/-, Puma -/-, and wild-type mice (Mysm1 -/- Puma +/- phenocopies Mysm1 -/-)."