IndraLab

Statements

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"In pancreatic cancer cell lines we determined that chloroquine and hydroxychloroquine block CXCL12 mediated signaling through the ERK pathway with downstream effects on both apoptosis and cell proliferation."
22319600
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"Second, our results indicate that chloroquine and hydroxychloroquine abrogate CXCL12 mediated anti-apoptosis (XREF_FIG), wherein pretreatment with chloroquine or hydroxychloroquine increased apoptosis in PANC-1 cells."
22319600
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"Furthermore, hydroxychloroquine inhibited CXCL12 induced receptor degradation."
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