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USP4 activates PTP4A3. 2 / 2
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"It was recently found that deubiquitinating enzyme USP4 promotes PRL-3 stabilization in colon cancer cells."

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"In addition, USP4, which is elevated in gastric and rectal cancer, interacts with PRL-3 and increases the stability of PRL-3, promoting NF-κB signaling and cell viability [51,60]."