IndraLab

Statements

CYLD inhibits TRAF2. 5 / 8
1 | 2 2
reach
"CYLD also inhibits TRAF2 and NEMO (NF-kappaB essential modulator, a regulatory subunit of IKK), and blocks NF-kappaB signaling downstream to TLR activation [176] [177] [178]."
| DOI
signor
"Cyld also interacts directly with tumour-necrosis factor receptor (tnfr)-associated factor 2 (traf2), an adaptor molecule involved in by members of the family of tnf/nerve growth factor receptors. (articolo-abstract)"
12917691
reach
"Similarly, de-ubiquitinating enzyme cylindromatosis (CYLD) inhibits NF-kappaB signaling via de-ubiquitination and inactivation of TNFR associated factor 2 (TRAF2) and TRAF6 [XREF_BIBR, XREF_BIBR]; de-ubiquitinating protease A20 inhibits NF-kappaB activation induced by Toll like receptor 4 (TLR4) via removing K63 linked polyubiquitin chains of TRAF6 [XREF_BIBR]."
27164085
sparser
"Similarly to active-site C601 CYLD mutants ( Trompouki et al. , 2003 ; this work), CYLD-D681G was unable to inhibit TRAF2- or TRAF6-mediated activation of NF- κ B and TNF α activation of JNK, and to[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
17851586
sparser
"CYLD also inhibits TRAF2 and NEMO (NF-κB essential modulator, a regulatory subunit of IKK), and blocks NF-κB signaling downstream to TLR activation [176] [177] [178] ."
| DOI