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USP9X activates cell migration. 12 / 12
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"Thus, the deubiquitination induced recycling of integrin alpha5beta1 mediated by USP9x promotes cell migration, while the degradative HD-PTP and UBAP1 pathway is required for ESCRT dependent lysosomal[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"Depletion of USP9X suppressed GBM cell migration, proliferation, and M2 macrophage polarization."
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"The negative regulation of USP9X destabilizes SMURF1 and inhibits SMURF1-dependent cell migration in breast cancer cells (80)."
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"Deubiquitinase USP9X promotes cell migration, invasion and inhibits apoptosis of human pancreatic cancer."
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"The outcomes of Transwell assays showed that hsa_circ_0024093 knockdown weakened the cell migration, which was restored in response to an augment in USP9X expression level; moreover, the restoration of cell migration induced by USP9X overexpression was partly offset by augmented expression of miR-889-3p but fully counteracted under co-upregulation of miR-889-3p and miR-4677-3p (Figure 6A)."
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"USP9X contributed to angiogenesis and promoted cell migration in MCL cells."
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"In addition, cell migration and invasion were promoted by USP9X overexpression."
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"Moreover, we found that USP9X contributed to angiogenesis and increased cell migration in MCL cells."
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"However, USP9X knockdown inhibited cell migration and invasion in Z-138 and Jeko-1 (Figure 4C, D)."
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"We found that both USP9X or EWS-FLI1 knockdown increased cell migration of TC32 cells ( Fig. 4 A and B) and A673 cells ( Supplementary Fig. 4 A-C )."
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"In addition, USP9X was also verified to contribute to angiogenesis and enhanced cell migration in MCL cells."
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"Cell migration and invasion were significantly inhibited by down-regulation of USP9X ."
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