IndraLab

Statements

BAP1 activates mutated ASXL1. 2 / 2
| 2
reach
"Mutant ASXL1 was reported to drive response to the BCL2 inhibitor venetoclax in vitro and a small molecule inhibitor of BAP1 inhibited mutant ASXL1-driven leukemic gene expression and impaired tumor growth in vivo."
36951160
reach
"Then, these effects were observed in primary leukaemia samples with ASXL1 mutation that BAP1 reduction significantly decreased the colony-forming capacity and promoted the differentiation of blast cel[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
34186160