IndraLab

Statements


OTUB1 inhibits Janus. 2 / 2
| 2

reach
"We further found that OTUB1 inhibited the Janus kinase (JAK)/signal transducer and activator of transcription (STAT) signaling pathway to regulate the growth of GBM."

reach
"Mechanistically, OTUB1 inhibited IFN-gamma-induced Janus kinase (JAK)/signal transducer and activator of transcription (STAT) signaling by K48 deubiquitination and stabilization of the JAK2 inhibitor suppressor of cytokine signaling 1 (SOCS1)."