IndraLab

Statements



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"Concomitant ablation of USP14 and UCHL5 strongly inhibits cell proliferation."

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"UCH37 depletion also decreases both cell proliferation and apoptosis induction in functional assays."

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"In our study, UCHL5 downregulation significantly suppressed both tumor growth in vivo and cell proliferation and migration in vitro."

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"Overexpression of UCHL5 enhances, while silencing of UCHL5 represses, cancer cell proliferation and migration by c-Myc, SLC25A19, and ICAM5 transformation via AKT/mTOR pathways."

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"All these results suggested that UCHL5 knockdown repressed ox-LDL-induced excessive proliferation, migration, inflammatory response as well as synthetic phenotype switching in VMSCs.To investigate the[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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"The CCK-8 assays showed that UCHL5 ablation significantly suppressed the proliferation rates of PAAD cells ( Fig. 3 D), whereas UCHL5 overexpression enhanced PAAD cells proliferation ( Fig. 3 E)."

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"As can be seen from Figure 5B,C, the colony formation and CCK-8 assay results show that SC79 similarly reverses the attenuated cell colony formation and proliferation caused by UCHL5 silencing."

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"We also found that UCHL5 downregulation significantly suppressed both tumor growth in vivo and cell proliferation and migration in vitro."