IndraLab

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Modified UCHL1 inhibits APP. 2 / 2

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"Furthermore, overexpression of UCHL1 reduces the production of Abeta by downregulating the protein level of beta-secretase and APP [XREF_BIBR, XREF_BIBR]."

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"Moreover, overexpression of UCHL1 reduces the levels of beta-secretase BACE1, and consequent BACE1 cleavage products (APP C-terminal fragment C99 and Abeta)."

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IndraLab

Statements

Modified UCHL1 inhibits APP. 2 / 2

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