IndraLab

Statements

KCNMA1 inhibits bradykinin. 5 / 5
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"Furthermore, glomus cells continue to release catetcholamines after BK channels are blocked by the BK channel toxin iberiotoxin (IbTX) (Pardal et al., 2000)."
16137743
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"The data in SCN also provide a framework for understanding the physiological relevance of BK channel inactivation, which is too slow to produce substantial BK current decay during a typical central nervous system action potential XREF_BIBR."
26940770
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"Expression of slo 1 has been shown to largely reduce or eliminate the BK current in larval and adult muscles, and neurons."
23638395
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"The other (27% of cells) had resting currents dominated by BK channels inhibited by the BK channel blocker penitrem A, but insensitive to both forskolin and the IK channel blocker clotrimazole."
23740188
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"These BK channels had a conductance of 276 pS, were activated by the elevation of both the transmembrane potential and intracellular calcium concentration ([Ca (2+)] (i)), and were completely blocked by the BK channel specific blocker paxilline (100 nM)."
20600663