IndraLab

Statements

LGI1 binds KCNA1. 3 / 3
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reach
"LGI1 antibodies bind to Kv1.1 at the presynaptic nerve terminals and lead to central sensitization."
38495247
sparser
"LGI1 also indirectly binds Kv1.1 VGKC (voltage-gated potassium channels), which is a major constituent of presynaptic A-type channels that modulate synaptic transmission in CNS neurons (Schulte et al., xref )."
23713523
sparser
"LGI1 associates specifically with Kv1.1 subunits in CNS presynaptic terminals ( Schulte et al., 2006 )."
35853356