IndraLab
Statements
Clondronate(2-) inhibits NLRP3. 1 / 1
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1
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"These results suggest that pDCs are the major cell population responsible for early IFN-α and IFN-β production and resistance to lethal YM infection in inflammasome-deficient mice.To exclude the possibility that macrophages and cDCs also contribute to early IFN-α and IFN-β production, we also depleted macrophages in Nlrp3 or Aim2 mice by intraperitoneal injection of clodronate liposome at 2 days before YM infection."