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12-HETE activates KCNMA1. 2 / 2

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"These results demonstrate that there is no observed allosteric product feedback with sLO-1 's endogenous products, however, the non endogenous product, 12-HETE, increased the substrate specificity of sLO-1 towards AA, when challenged with an LA/AA mixture."

19716306

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"12-HETE, a product of the lipoxygenase isoform 12-LO expressed in the arterial wall, is a vasodilator and enhances BK channel activity in vascular smooth muscle (130)."

21895549

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IndraLab

Statements

12-HETE activates KCNMA1. 2 / 2

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