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KCNB1 activates exocytosis. 3 / 3
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"However, knockdown of KCNB1, but not KCNB2, impairs depolarization induced exocytosis in human beta-cells (XREF_FIG), which is consistent with the divergent C-terminal homology and an inability of Kv2.2 to bind the syntaxin 1A/SNAP -25 complex."
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"[7] therefore went on to demonstrate that loss of Kv2.1 reduced exocytosis and impaired presynaptic Ca 2+ influx, and that specific motifs in the VAP-binding, cluster inducing C-terminal tail of the c[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"To determine if the loss of Kv2.1 impairs exocytosis through activation of STIM1, we utilized shRNA to KD expression levels of both Kv2.1 and STIM1."
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