IndraLab

Statements

OTUD7B activates miR-500. 3 / 3
| 3
reach
"Importantly, the repressive effect of antagomiR-500 on NF-kappaB activity and BCL2L1, CCND1 expression were potently antagonised by individual silencing of CYLD, TAX1BP1, or OTUD7B (XREF_SUPPLEMENTARY), indicating that CYLD, TAX1BP1, and OTUD7B are functionally relevant effectors of miR-500 in NF-kappaB activation."
25595906
reach
"Taken together, our results demonstrate that CYLD, TAX1BP1, and OTUD7B are bona fide targets of miR-500."
25595906
reach
"Using the TargetScan program, we found that CYLD, OTUD7B, and the A20 complex component TAX1BP1, which function as critical negative regulatory genes by deconjugating K63-polyubiquitin chains from RIP1 [XREF_BIBR, XREF_BIBR], might be potential targets of miR-500."
25595906