IndraLab

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EIF3F inhibits cytokinesis. 2 / 2
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"We also showed that silencing of eIF3f promotes both cap dependent and cap-independent and internal ribosome entry site (IRES)-dependent translation and cytokinesis defects."
22457825
reach
"In our current study, we found evidence that stable knockdown of eIF3f in normal human pancreatic ductal epithelial cells increased cell size, nuclear pleomorphism, cytokinesis defects, cell proliferation, clonogenicity, apoptotic resistance, migration, and formation of 3-dimensional irregular masses."
22457825