IndraLab

Statements

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"Mechanistically, EGCG was revealed to repress the activation of macrophage NLRP3 inflammasome, a critical trigger of HBV-induced liver fibrosis."
37122751
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"Citral and epigallocatechin-3-gallate (EGCG), both bioactive compounds derived from traditional Chinese medicine, prevent NLRP3 activation in vivo in mouse models of lupus and improve nephritis by protecting cells from oxidative damage."
28374568
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"Furthermore, EGCG inhibited renal NLRP3 inflammasome activity, and the expressions of NLRP3, caspase-1, and IL-1beta were also reduced, possibly due to the EGCG induced attenuation of NFkappaB pathway activity."
27672241
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"EGCG inhibited NLRP3 inflammation via de novo synthesis of mitochondrial DNA and generation of reactive oxygen species in primary mouse macrophages."
33534121
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"The polyphenolic Epigallocatechin-3 Gallate (EGCG) has been shown to prevent acute gout through its anti-inflammatory activity by suppressing the activation of the NLRP3 inflammasome, acting as a modulator of Lysine Acetyl Transferase (KAT) (50)."
34603340
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"EGCG inhibits NLRP3 inflammation by blocking MSU crystal induced production of caspase-1 (p10) and interleukin-1beta in primary mouse macrophages."
33534121