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OTUB2-C51S deubiquitinates RIPK3. 2 / 2
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"We found that the enzymatically inactive OTUB2 C51S mutant failed to deubiquitinate RIPK3, demonstrating that OTUB2 stabilizes RIPK3 through its enzymatic activity."

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"The OTUB2 C51S mutant, which was deprived of the enzymatic activity, failed to K48 deubiquitinate RIPK3 (Fig. 5J)."