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USP44 inhibits Wnt. 2 / 2

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"USP44 suppresses proliferation and enhances apoptosis in colorectal cancer cells by inactivating Wnt and beta-catenin pathway via Axin1 deubiquitination."

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"We found that USP44 overexpression increased Axin1 protein while decreased beta-catenin, c-myc and Cyclin D1 proteins, suggesting that USP44 inhibited the activation of Wnt and beta-catenin pathway."

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IndraLab

Statements

USP44 inhibits Wnt. 2 / 2

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