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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

USP44 inhibits Wnt. 2 / 2

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"USP44 suppresses proliferation and enhances apoptosis in colorectal cancer cells by inactivating Wnt and beta-catenin pathway via Axin1 deubiquitination."

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"We found that USP44 overexpression increased Axin1 protein while decreased beta-catenin, c-myc and Cyclin D1 proteins, suggesting that USP44 inhibited the activation of Wnt and beta-catenin pathway."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...